Bruno Allolio Selected Research

Adrenal Insufficiency (Adrenal Gland Hypofunction)

3/2015	Extensive expertise in endocrinology. Adrenal crisis.
7/2014	Suspected metastatic adrenocortical carcinoma revealing as pulmonary Kaposi sarcoma in adrenal Cushing's syndrome.
8/2013	Subcutaneous hydrocortisone administration for emergency use in adrenal insufficiency.
1/2013	Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement.
3/2010	Influence of hydrocortisone dosage scheme on health-related quality of life in patients with adrenal insufficiency.
4/2009	Therapeutic management of adrenal insufficiency.
12/2008	Impaired subjective health status in chronic adrenal insufficiency: impact of different glucocorticoid replacement regimens.
11/2007	Mifepristone (RU 486) in Cushing's syndrome.
10/2007	Impaired subjective health status in 256 patients with adrenal insufficiency on standard therapy based on cross-sectional analysis.
4/2006	Quality of glucocorticoid replacement in adrenal insufficiency: clinical assessment vs. timed serum cortisol measurements.

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Bruno Allolio Research Topics

Disease

33	Adrenocortical Carcinoma 11/2015 - 01/2005
30	Neoplasms (Cancer) 03/2016 - 05/2003
18	Adenoma (Adenomas) 01/2016 - 01/2005
15	Adrenal Insufficiency (Adrenal Gland Hypofunction) 03/2015 - 09/2002
8	Body Weight (Weight, Body) 03/2013 - 10/2003
7	Adrenocortical Adenoma (Disease, Conn's) 03/2016 - 01/2005
7	Heart Failure 03/2015 - 01/2007
6	Hyponatremia 07/2017 - 01/2009
6	Hyperaldosteronism (Conn Syndrome) 11/2015 - 02/2012
6	Cushing Syndrome 10/2014 - 11/2007
6	Neoplasm Metastasis (Metastasis) 07/2014 - 11/2006
4	Hyperplasia 10/2014 - 01/2005
3	ACTH-Secreting Pituitary Adenoma 03/2016 - 10/2015
3	Pituitary ACTH Hypersecretion 01/2016 - 01/2015
3	Carcinoma (Carcinomatosis) 08/2015 - 06/2006
3	Hypertension (High Blood Pressure) 04/2015 - 04/2013
3	Adrenal Cortex Neoplasms (Adrenocortical Cancer) 01/2013 - 06/2006
3	Hypertrophy 04/2011 - 02/2003
2	Autoimmune Diseases (Autoimmune Disease) 02/2016 - 01/2011
2	Systolic Heart Failure 01/2016 - 04/2007
2	Pituitary Neoplasms (Pituitary Adenoma) 01/2016 - 10/2015
2	Polydipsia 06/2015 - 05/2011
2	Polyuria 06/2015 - 05/2011
2	Hypotension (Low Blood Pressure) 03/2015 - 01/2015
2	Infections 03/2015 - 07/2012
2	Addison Disease (Addison's Disease) 01/2015 - 06/2009
2	Hypothyroidism 06/2014 - 03/2010
2	Disease Progression 04/2014 - 06/2012
2	Chronic Kidney Failure (Chronic Renal Failure) 02/2014 - 04/2011
2	Sudden Death 02/2013 - 04/2011
2	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2013 - 03/2010
2	Psychogenic Polydipsia 05/2011 - 01/2009
2	Type 2 Diabetes Mellitus (MODY) 04/2011 - 09/2009
2	Pain (Aches) 12/2008 - 02/2005
2	Coronary Artery Disease (Coronary Atherosclerosis) 07/2008 - 02/2003
2	Myocardial Infarction 01/2007 - 02/2003
2	Pheochromocytoma 12/2006 - 07/2005
2	Sepsis (Septicemia) 07/2006 - 11/2005
2	Reperfusion Injury 10/2003 - 09/2002
2	Ischemia 10/2003 - 09/2002
1	Water-Electrolyte Imbalance 07/2017
1	Chronic Renal Insufficiency 01/2017

Drug/Important Bio-Agent (IBA)

26	Hydrocortisone (Cortisol)FDA LinkGeneric 03/2016 - 01/2005
14	GlucocorticoidsIBA 01/2013 - 09/2002
13	Mitotane (Lysodren)FDA Link 11/2015 - 06/2006
13	AldosteroneIBA 04/2015 - 01/2005
9	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2016 - 03/2005
8	Proteins (Proteins, Gene)FDA Link 03/2016 - 05/2003
7	SteroidsIBA 11/2015 - 02/2003
6	SodiumIBA 07/2017 - 04/2007
6	Hormones (Hormone)IBA 11/2015 - 02/2002
6	AndrogensIBA 10/2014 - 09/2002
5	Arginine Vasopressin (Argipressin)IBA 01/2017 - 04/2011
5	Messenger RNA (mRNA)IBA 08/2015 - 02/2003
5	Dehydroepiandrosterone (DHEA)IBA 03/2010 - 09/2002
4	Biomarkers (Surrogate Marker)IBA 10/2015 - 11/2009
4	MineralocorticoidsIBA 01/2015 - 05/2003
4	EnzymesIBA 09/2009 - 05/2003
3	Glucose (Dextrose)FDA LinkGeneric 11/2015 - 09/2009
3	LipidsIBA 11/2015 - 12/2006
3	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 03/2015 - 04/2007
3	ElectrolytesIBA 01/2015 - 06/2008
3	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 12/2014 - 03/2014
3	Dexamethasone (Maxidex)FDA LinkGeneric 10/2014 - 11/2007
3	iodophenyl metomidateIBA 07/2013 - 06/2008
3	CateninsIBA 12/2012 - 01/2011
3	Testosterone (Sustanon)FDA Link 06/2011 - 02/2003
3	Capsules (Microcapsules)IBA 11/2010 - 06/2006
2	Ubiquitin-Specific ProteasesIBA 01/2016 - 10/2015
2	Peptides (Polypeptides)IBA 06/2015 - 05/2003
2	ErbB Receptors (EGF Receptor)IBA 01/2015 - 12/2010
2	SaltsIBA 01/2015 - 07/2012
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 04/2014 - 07/2009
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2014 - 05/2003
2	Cytochrome P-450 CYP3AIBA 01/2013 - 11/2011
2	Phosphotransferases (Kinase)IBA 12/2012 - 07/2009
2	Sunitinib (Sutent)FDA Link 10/2012 - 01/2011
2	Cisplatin (Platino)FDA LinkGeneric 06/2012 - 02/2010
2	Etoposide (VP 16)FDA LinkGeneric 06/2012 - 02/2010
2	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2012 - 02/2010
2	Streptozocin (Streptozotocin)FDA Link 06/2012 - 02/2010
2	Pharmaceutical PreparationsIBA 11/2011 - 11/2007
2	Tyrosine Kinase InhibitorsIBA 01/2011 - 07/2009
2	Prednisolone (Predate)FDA LinkGeneric 01/2011 - 12/2008
2	AdiponectinIBA 09/2009 - 07/2008
2	Estrogens (Estrogen)FDA Link 01/2007 - 09/2002
2	Estradiol (Delestrogen)FDA LinkGeneric 01/2007 - 09/2002
2	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 08/2006 - 05/2003
2	CalciumIBA 10/2003 - 02/2002
2	BuffersIBA 10/2003 - 09/2002
1	Edetic Acid (EDTA)FDA Link 07/2017
1	Adrenal Cortex Hormones (Corticosteroids)IBA 02/2016

Therapy/Procedure

19	Therapeutics 03/2015 - 05/2003
5	Adrenalectomy 04/2015 - 01/2006
5	Radiotherapy 05/2011 - 06/2006
2	Critical Care (Surgical Intensive Care) 07/2017 - 07/2010
2	Drug Tapering 01/2015 - 01/2011
2	Renal Dialysis (Hemodialysis) 06/2014 - 04/2011
2	Lymph Node Excision (Lymph Node Dissection) 04/2013 - 02/2012
2	Adjuvant Radiotherapy 07/2009 - 11/2006